Listar Microbiología por título
Mostrando ítems 1109-1128 de 1168
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Ultrastructural alterations in mouse capillary blood vessels after experimental injection of venom from the snake Bothrops asper (Terciopelo)
(1992-10)Histological and ultrastructural alterations in capillary blood vessels were studied at various time intervals after im injection of 50 micrograms of Bothrops asper snake venom in mouse gastrocnemius muscle. Hemorrhage was ... -
Understanding and confronting snakebite envenoming: The harvest of cooperation
(2016-01)During 45 years, the Instituto Clodomiro Picado (ICP, University of Costa Rica) has developed an ambitious scientific, technological, productive, and social program aimed at providing a better understanding of snakes and ... -
Understanding structural and functional aspects of PII snake venom metalloproteinases: Characterization of BlatH1, a hemorrhagic dimeric enzyme from the venom of Bothriechis lateralis
(2014-06)A new homodimeric PII metalloproteinase, named BlatH1, was purified from the venom of the Central American arboreal viperid snake Bothriechis lateralis by a combination of anion-exchange chromatography, hydrophobic interaction ... -
Unexpected Functional Divergence of Bat Influenza Virus NS1 Proteins
(2018-02-12)Recently, two influenza A virus (FLUAV) genomes were identified in Central and South American bats. These sequences exhibit notable divergence from classical FLUAV counterparts, and functionally, bat FLUAV glycoproteins ... -
Unity makes strength: exploring intra and interspecies toxin synergism between phospholipases A2 and cytotoxins
(2020)Toxin synergism is a complex biochemical phenomenon, where different animal venom proteins interact either directly or indirectly to potentiate toxicity to a level that is above the sum of the toxicities of the individual ... -
Unravelling a vicious circle: animal feed marketed in Costa Rica contains irregular concentrations of tetracyclines and abundant oxytetracycline-resistant Gram-positive bacteria
(2014-04)Diverse tetracyclines are used to prevent and control bacterial infections in livestock and farmed fish. These drugs are administered through the diet, but farmers seldom check whether feed contains antibiotic-resistant ... -
Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms
(2018-06)Snakebite envenoming by viperid species, and by some elapids, is characterized by a complex pattern of tissue damage at the anatomical site of venom injection. In severe cases, tissue destruction may be so extensive as ... -
Unveiling the nature of black mamba (Dendroaspis polylepis) venom through venomics and antivenom immunoprofiling: identification of key toxin targets for antivenom development.
(2015-04-24)The venom proteome of the black mamba, Dendroaspis polylepis, from Eastern Africa, was, for the first time, characterized. Forty- different proteins and one nucleoside were identified or assigned to protein families. The ... -
Urban structure and dengue incidence in Puntarenas, Costa Rica
(2009-07-15)Dengue is currently the most important arboviral disease globally and is usually associated with built environments in tropical areas. Remotely sensed information can facilitate the study of urban mosquito-borne diseases ... -
Urokinase plasminogen activator receptor is expressed in invasive cells in gastric carcinomas from high- and low-risk countries
(International Journal of Cancer 146 año 2009 p. 405–415, 2009-07-16)Gastric cancer is the second cancer causing death worldwide. Both incidence and mortality rates vary according to geographical regions. The receptor for urokinase plasminogen activator (uPAR) is involved in extracellular ... -
Using Geographical Information Systems to Identify Populations in Need of Improved Accessibility to Antivenom Treatment for Snakebite Envenoming in Costa Rica
(2013-01-31)INTRODUCTION: Snakebite accidents are an important health problem in rural areas of tropical countries worldwide, including Costa Rica, where most bites are caused by the pit-viper Bothrops asper. The treatment of these ... -
Uso de secuenciación de Nueva Generación (NGS) para el diagnóstico de alteraciones hemostáticas hereditarias
(2021)Los desórdenes de sangrado pueden deberse a deficiencias en los factores de coagulación, a desórdenes plaquetarios o a defectos en el sistema fibrinolítico. Son un grupo heterogéneo de desórdenes causados por variantes de ... -
Uso del “Pesticide Impact Rating Index” (PIRI) para estimar la peligrosidad del uso de plaguicidas en el cultivo de cebolla (Allium cepa L.)
(2014)Se utilizó el programa “Pesticide Impact Rating Index” (PIRI) para estimar la peligrosidad del uso de 30 plaguicidas en el cultivo de cebolla (Allium cepa L.) para la calidad del agua de la quebrada Sanatorio, ubicada ... -
Utilidad de la canasta básica alimentaria como indicador socioeconómico
(1985)En el presente trabajo se destaca la importancia y utilidad de Ia Canasta Básica Alimentaria como fuente de información y como detector de situaciones críticas en aspectos sociales. Para ello, se realizó un análisis del ... -
Utilidad de las células T con receptor de antígeno quimerico (CAR T) en el tratamiento de las neoplasias hematológicas
(2021)Objetivo General: Analizar la utilidad de las células T con receptor de antígeno quimérico (CAR T) en el tratamiento de las neoplasias hematológicas. -
Utilidad de los péptidos sintéticos en estudios de estructura-función e identificación de epitopos en toxinas
(Bruno Lomonte. (2014). Utilidad de los péptidos sintéticos en estudios de estructura-función e identificación de epitopos en toxinas. Cuba: RED BIOTOX-CYTED. pp.71-80, 2014)Los péptidos sintéticos han ganado un lugar relevante dentro de la “caja de herramientas” de la investigación biomédica actual. Las técnicas de síntesis automatizada y el costo decreciente de los procesos, unidas a mejoras ... -
Validación de la técnica QF-PCR para el diagnóstico de cromosomopatías en Costa Rica
(2008)Introducción. Las cromosomopatías autosómicas más frecuentes son las trisomías de los cromosomas 21, 18 y 13. En Costa Rica, el diagnóstico de anomalías cromosómicas fetales y neonatales se realiza solo mediante el ... -
Validación de una técnica de detección para Listeria monocytogenes en leche, embutidos y queso mediante la implementación de PCR punto final basado en los pares de iniciadores LM8, LM13 y LM20
(2019-10)Listeria es un género que se puede ubicar en muchos sitios como suelo, agua no tratada, superficies, etc. En este género sobresale Listeria monocytogenes como un patógeno de transmisión alimentaria de importancia en la ...