Listar Microbiología por título
Mostrando ítems 130-149 de 1168
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Asociación del polimorfismo del codon 72 del gen P53 con el riesgo de cáncer gástrico en una población de alto riesgo de Costa Rica
(Revista de Biología Tropical 53 (3-4): 317-324, 2005, 2005-10-03)El cáncer gástrico es la segunda causa de muerte por cáncer en el mundo. Varios factores han sido asociados con el riesgo de llegar a desarrollarlo, entre ellos la predisposición genética. El gen p53 presenta un polimorfismo ... -
Assessing a 6-h endpoint observation time in the lethality neutralization assay used to evaluate the preclinical efficacy of snake antivenoms
(2021-11)The lethality neutralization assay in mice is the gold standard for the evaluation of the preclinical efficacy and specification fulfillment of snake antivenoms. However, owing to the animal suffering involved, this assay ... -
Assessing endotoxins in equine-derived snake antivenoms: Comparison of the USP pyrogen test and the Limulus Amoebocyte Lysate assay (LAL)
(2015-08-29)Snake antivenoms are parenterally administered; therefore, endotoxin content must be strictly controlled. Following international indications to calculate endotoxin limits, it was determined that antivenom doses between ... -
Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics
(2013-07)The assessment of the capacity of antivenoms to neutralize the lethal activity of snake venoms is the gold standard in the preclinical analysis of antivenom efficacy, and is routinely performed by manufacturers and quality ... -
Assessment of acute toxicity of carbofuran in Macrobrachium olfersii (Wiegmann, 1836) at different temperature levels
(2013-07-11)Carbofuran (2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate; C12H15NO3) is one of the most toxic carbamate pesticides. For acute toxicity of carbofuran, juveniles of Macrobrachium olfersii were exposed to different ... -
Assessment of metalloproteinase inhibitors clodronate and doxycycline in the neutralization of hemorrhage and coagulopathy induced by Bothrops asper snake venom
(2008-12-01)Snake venom metalloproteinases (SVMPs) play a prominent role in the local and systemic manifestations of viperid snakebite envenomations. Thus, the possibility of using metalloproteinase inhibitors in the treatment of these ... -
Assessment of microbial communities associated with the gut and feeding substrate of three xylophagous coleopteran families with emphasis on cellulose-degrading bacteria
(2019-11)The current energy crisis and depletion of fossil fuel reserves has encouraged research for new alternatives. Degradation of plant material by enzymatic reactions represents an important strategy to obtain affordable and ... -
Assessment of the viral safety of antivenoms fractionated from equine plasma
(2004-09)Antivenoms are preparations of intact or fragmented (F(ab')2 or Fab) immunoglobulin G (IgG) used in human medicine to treat the severe envenomings resulting from the bites and stings of various animals, such as snakes, ... -
Associations between urban structure and Aedes aegypti larval habitats in Puntarenas, Costa Rica
(2008-12)Geospatial technologies have been increasingly applied to study vector-borne diseases, although their use in urban setting has been limited. In this study, high-resolution satellite imagery from QuickBird was analyzed to ... -
Autocatalytic acylation of phospholipase-like myotoxins
(1995-04)Several snake venoms contain a phospholipase A2 in which position 49 in the active site is occupied by a lysine or a serine instead of the aspartate residue normally found. Although these proteins do not bind Ca2+ and are ... -
Avances de la bioinformática en Costa Rica: Vista retrospectiva y perspectivas
(2021-11-09)Introducción: La disciplina científica de la bioinformática tiene el potencial de generar aplicaciones innovadoras para las sociedades humanas. Costa Rica, pequeña en tamaño y población en comparación con otros países de ... -
Avances en el conocimiento de la diarrea viral
(Infectología 2:151-160, 1981)Hasta la segunda década de este siglo, la diarrea había encabezado las causas de muerte durante el primer año de vida, aún en los países desarrollados; en estas naciones, tal problema y sus complicaciones disminuyó ... -
Backbone Flexibility Controls the Activity and Specificity of a Protein−Protein Interface: Specificity in Snake Venom Metalloproteases
(2010-07-09)Protein-protein interfaces have crucial functions in many biological processes. The large interaction areas of such interfaces show complex interaction motifs. Even more challenging is the understanding of (multi)specificity ... -
Bacterial communities in residential wastewater treatment plants are physiologically adapted to high concentrations of quaternary ammonium compounds
(2023-08-28)Benzalkonium chloride (BAC) is a quaternary ammonium compound (QAC) widely used as the active ingredient of disinfectants. Its excessive discharge into wastewater is constant and in high concentrations, likely affecting ... -
Bacterial Sphingomyelinases and Phospholipases as Virulence Factors
(2016-06-15)Bacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases which are usually surface associated or secreted by a wide variety of Gram-positive and Gram-negative bacteria. These enzymes hydrolyze ... -
Bacterias multirresistentes a los antibióticos aisladas de niños hospitalizados de "alto riesgo"
(Revista Médica del Hospital Nacioanl de Niños Dr. Carlos Sáenz, 1978)Between January and September, 1977, 43 strains of Klebslella-Enterobac-ter, 17 of Pseudomonas and 6 of Escherlchla coli —all resistant to several drugs—were isolated from 66 children hospitalized in the National Children's ... -
Bactericidal activity of Lys49 and Asp49 myotoxic phospholipases A2 from Bothrops asper snake venom: synthetic Lys49 myotoxin II-(115-129)-peptide identifies its bactericidal region
(1998)Mammalian group-II phospholipases A2 (PLA2) of inflammatory fluids display bactericidal properties, which are dependent on their enzymatic activity. This study shows that myotoxins II (Lys49) and III (Asp49), two group-II ... -
Bactericidal and anti-endotoxic properties of short cationic peptides derived from a snake venom Lys49 phospholipase A2
(2005)The activities of short synthetic, nonhemolytic peptides derived from the C-terminal region of myotoxin II, a catalytically inactive phospholipase A2 homologue present in the venom of the snake Bothrops asper, have been ... -
Bases moleculares del reconocimiento de antígenos
(1999)Aunque todos los organismos pertenecientes al reino animal poseen una serie de mecanismos inmunitarios que persiguen mantener su integridad y rechazar la invasión de material foráneo, solo los vertebrados cuentan con un ...