Browsing Microbiología by Title
Now showing items 739-758 of 808
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Tamizaje de Diabetes Mellitus tipo 2 en atención primaria
(Acta Médica Costarricense 48(1) p 17-23, 2006-01)Introducción: Actualmente en Costa Rica debería considerarse la Diabetes Mellitus tipo 2, un problema de salud pública, por el impacto de sus complicaciones crónicas tanto en el ámbito individual y familiar, como en lo ... -
Tecnologías de secuenciación de nueva generación: principios, aplicaciones y escenario en Costa Rica
(2017-12)La secuenciación de nueva generación (NGS, por sus siglas en inglés) corresponde a un grupo de tecnologías originadas a mediados de la década del 2000 por la necesidad de mejorar la capacidad de procesamiento y reducción ... -
Ten simple rules for aspiring scientists in a low-income country
(PLOS Computational Biology, vol. 4, n. 5, e1000024, 2008, 2008)Being a scientist entails a common set of characteristics. Admiring nature and having concern for social issues; possessing a strong academic background, team work abilities, honesty, discipline, skepticism, communication ... -
Terapia larval con Lucilia eximia (Diptera: Calliphoridae) de Costa Rica en un modelo experimental
(2014-06-01)Con el fin de analizar la aceleración en la solución de heridas dérmicas mediante el tratamiento con larvas de Lucilia eximia (Diptera: Calliphoridae), se generaron úlceras en piel en parejas de ratas mediante inoculación ... -
The ability of specific antivenom and low temperature to inhibit the myotoxicity and neuromuscular block induced by Micrurus nigrocinctus venom
(1995-05)In the isolated mouse diaphragm preparation, Micrurus nigrocinctus venom produced a dose-dependent contracture and blockade of the contractile response to direct and indirect electrical stimulation of the muscle. This ... -
The amino acid sequence of a myotoxic phospholipase from the venom of Bothrops asper
(1990)A myotoxic, basic phospholipase A2 (pI greater than 9.5) with anticoagulant activity has been purified from the venom of Bothrops asper, and its amino acid sequence determined by automated Edman degradation. It is distinct ... -
The analgesics morphine and tramadol do not alter the acute toxicity induced by Bothrops asper snake venom in mice
(2014-04)Analgesics tramadol and morphine were used in mice injected with Bothrops asper venom. Analgesics did not alter the acute toxicity of B. asper venom in mice. Precautionary (prophylactic) analgesia should be ... -
The C-terminal region of a Lys49 myotoxin mediates Ca2þ influx in C2C12 myotubes
(2010-02)Myotoxins are abundant components of snake venoms, being a significant public health problem worldwide. Among them, Lys49 phospholipase A2 homologue myotoxins cause extensive necrosis in skeletal muscle tissue. Their ... -
The dynamics of local tissue damage induced by Bothrops asper snake venom and myotoxin II on the mouse cremaster muscle: an intravital and electron microscopic study
(1994-01)The acute tissue damaging effects of Bothrops riper snake venom and a myotoxic Lys-49 phospholipase A2 (myotoxin In on the mouse cremaster muscle were studied by intravital and electron microscopy. Both venom and myotoxin ... -
The effect of myotoxins isolated from Bothrops snake venoms on multilamellar liposomes: relationship to phospholipase A2, anticoagulant and myotoxic activities
(1991-12)The effect of four myotoxins isolated from Bothrops snake venoms on the release of peroxidase trapped in large multilamellar liposomes was studied and correlated to their phospholipase A2, myotoxic and anticoagulant ... -
The effects of human movement on the persistence of vector-borne diseases
(2009-06)With the recent resurgence of vector-borne diseases due to urbanization and development there is an urgent need to understand the dynamics of vector-borne diseases in rapidly changing urban environments. For example, many ... -
The Global Snake Bite Initiative: an antidote for snake bite
(2010-01-02)Clinicians have for a long time witnessed the tragedy of injury, disability, and death from snake bite that is a daily occurrence in many parts of Africa, Asia, and Latin America. To many people living in these ... -
The lethality test used for estimating the potency of antivenoms against Bothrops asper snake venom: Pathophysiological mechanisms, prophylactic analgesia, and a surrogate in vitro assay
(2015-01)The potency of antivenoms is assessed by analyzing the neutralization of venom-induced lethality, and is expressed as the Median Effective Dose (ED50). The present study was designed to investigate the pathophysiological ... -
The need for an integrated approach in confronting snakebite envenoming in Latin America: the relevance of endogenous scientific and technological research
(2016)Snakebite envenomings constitute a serious public health problem on a global level, especially in Africa, Asia and Latin America. In our Latin American region, it is estimated that at least 70,000 snakebite cases occur ... -
The Need for Full Integration of Snakebite Envenoming within a Global Strategy to Combat the Neglected Tropical Diseases: The Way Forward
(2013-06-13)Snakebite envenoming constitutes a serious medical condition that primarily affects residents of rural communities in Africa, Asia, Latin America, and New Guinea [1], [2]. It is an occupational, environmental, and domestic ... -
The Novel Phages phiCD5763 and phiCD2955 Represent Two Groups of Big Plasmidial Siphoviridae Phages of Clostridium difficile
(2018-01)Until recently, Clostridium difficile phages were limited to Myoviruses and Siphoviruses of medium genome length (32–57 kb). Here we report the finding of phiCD5763, a Siphovirus with a large extrachromosomal circular ... -
The Phospholipase A2 Homologues of Snake Venoms: Biological Activities and Their Possible Adaptive Roles
(2009)A particular subgroup of toxins with phospholipase A2 (PLA2) structure, but devoid of this enzymatic activity, is commonly found in the venoms of snakes of the family Viperidae, and known as the PLA2 homologues. Among ... -
The snake venom metalloproteinase BaP1 induces joint hypernociception through TNF-α and PGE2-dependent mechanisms
(2007-08)BACKGROUND AND PURPOSE: Matrix metalloproteinases (MMPs) have been implicated in joint tissue destruction in arthritis. However, MMPs have not been assigned a role in joint pain. We investigated the ability of BaP1, a ... -
The STR polymorphism (AAAAT)n within the intron 1 of the tumor protein 53 (TP53) locus in 17 populations of different ethnic groups of Africa, America, Asia and Europe
(Revista de Biología Tropical, 52(3):645-657, 2004)The SIR (A.AAAT). within intron 1 of the TP53 Locus was screened in 17 populations from 3 main ethnic groups: Europeans, Asiatics, and Africans. and from the hybrid population of Costa Rica (1968 samples). Three alleles, ...