Browsing Microbiología by Title
Now showing items 399-418 of 878
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Gene Expression Dynamics Induced by Ciprofloxacin and Loss of LexA Function in Pseudomonas aeruginosa PAO1 Using Data Mining and Network Analysis
(2018)Pseudomonas aeruginosa is an opportunistic pathogen that causes a variety of infections in humans and frequently develops mechanisms of resistance to antibiotics, which makes its treatment difficult. In this study we ... -
Genetic variation of the Y chromosome in Chibcha-Speaking amerindians of Costa Rica and Panama
(Human Biology 77(1): 71-91, 2005)Genetic variation of the Y chromosome in five Chibchan tribes (Bribri, Cabecar, Guaymi, Huetar, and Teribe) of Costa Rica and Panama was analyzed using six microsatellite loci (DYS 19, DYS389A, DYS389B, DYS390, DYS391, and ... -
Genetic, dietary, and other lifestyle determinants of serum homocysteine levels in young adults in Costa Rica
(2005)Objective: Elevated serum total homocysteine (tHcy) is considered an independent risk factor for cardiovascular disease. The objective of this study was to develop the first-ever information on the prevalence of ... -
Geographical variability of the venoms of four populations of Bothrops asper from Panama: Toxicological analysis and neutralization by a polyvalent antivenom
(2017-06)Bothrops asper is the medically most important venomous snake in Central America. In Panama, the country having the highest incidence of snakebites in Latin America, B. asper is widely distributed throughout the country ... -
Global genetic diversity of Aedes aegypti
(2016-11)Mosquitoes, especially Aedes aegypti, are becoming important models for studying invasion biology. We characterized genetic variation at 12 microsatellite loci in 79 populations of Ae. aegypti from 30 countries in six ... -
Group-II phospholipase A2 enzymes
(2015-05)Phospholipase A2 are esterolytic enzymes that catalyze the hydrolysis of 1,2-diacyl-3-sn-glycerophospholipids at the C2 position, resulting in the formation of lysophospholipids and free fatty acid. They constitute one of ... -
Guía para el estudio de la taxonomía y ecología de Myxomycetes
(2020-06-17)Los Myxomycetes, también llamados hongos mucilaginosos plasmodiales, son un grupo de organismos eucariotas directamente relacionados con los Protozoos, por lo que también se les conoce como Mycetozoa. Están presentes ... -
Hacia una mayor integración de las ciencias naturales y las ciencias sociales: análisis de un caso relacionado con un problema de salud pública
(2009)Se discute la conveniencia de promover una interacción y un diálogo productivo entre las ciencias naturales, las ciencias sociales y las tecnologías. El tema se analiza alrededor del caso de un problema de salud: los ... -
Hallazgos histopatológicos asociados a la presencia de arbovirus (chikungunya, zika, dengue, virus del nilo occidental) en murciélagos y aves silvestres en ambientes rurales domiciliares y peridomiciliares
(2020)Los arbovirus son virus transmitidos por vectores artrópodos. En Costa Rica, circulan algunos como el Dengue, Zika, Chikungunya y Nilo occidental. Los arbovirus poseen dos ciclos ecológicos diferentes para lograr mantenerse ... -
Hemorrhage Caused by Snake Venom Metalloproteinases: A Journey of Discovery and Understanding
(2016-03-26)The historical development of discoveries and conceptual frames for understanding the hemorrhagic activity induced by viperid snake venoms and by hemorrhagic metalloproteinases (SVMPs) present in these venoms is reviewed. ... -
Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damage
(2005-06-15)Zinc-dependent metalloproteinases are responsible for the hemorrhagic activity characteristic of viperid snake venoms. Snake venom metalloproteinases (SVMPs) are classified in various groups (P-I–IV), according to their ... -
Hemostatic effects induced by Thalassophryne nattereri fish venom: a model of endothelium-mediated blood flow impairment.
(2002-08)Accidents by Thalassophryne nattereri fish venom are characterised by severe local symptoms and signs including pain of fast onset, oedema and necrosis with impaired muscle regeneration. These effects have been related to ... -
Heterogeneidad clonal en epimastigotos de una cepa centroamericana de Trypanosoma cruzi (Kinetoplastida: Trypanosomatidae)
(2002)El fenómeno de heterogeneidad clonal fue evaluado en una cepa centroamericana de Trypanosoma cruzi (San Salvador) en un sistema de cultivo en macrófagos. Cuatro clones denominados Clon 9, Clon 10, Clon 11 y Clon 12 fueron ... -
High quality 3C de novo assembly and annotation of a multidrug resistant ST-111 Pseudomonas aeruginosa genome: Benchmark of hybrid and non-hybrid assemblers
(2020)Genotyping methods and genome sequencing are indispensable to reveal genomic structure of bacterial species displaying high level of genome plasticity. However, reconstruction of genome or assembly is not straightforward ... -
High resolution analysis of snake venom metalloproteinase (SVMP) peptide bond cleavage specificity using proteome based peptide libraries and mass spectrometry
(2011-04-01)Both serine and metalloproteinases have been shown to play the role of toxins in the venoms of many snakes. Determination of the natural protein substrates of these toxins is an important feature in the toxinological ... -
High-density peptide microarray exploration of the antibody response in a rabbit immunized with a neurotoxic venom fraction
(2017-11)Polyvalent snakebite antivenoms derive their therapeutic success from the ability of their antibodies to neutralize venom toxins across multiple snake species. This ability results from a production process involving ... -
High-Resolution Crystal Structure of the Snake Venom Metalloproteinase BaP1 Complexed with a Peptidomimetic: Insight into Inhibitor Binding
(2009-07-07)BaP1, a zinc-dependent endopeptidase belonging to the P-I class of snake venom metalloproteinases, exerts multiple tissue-damaging activities, leading to hemorrhage, myonecrosis, dermonecrosis, blistering, and edema. ... -
High-throughput immuno-profiling of mamba (Dendroaspis) venom toxin epitopes using high-density peptide microarrays
(2016-11-08)Snakebite envenoming is a serious condition requiring medical attention and administration of antivenom. Current antivenoms are antibody preparations obtained from the plasma of animals immunised with whole venom(s) and ... -
Highly individual patterns of virus‑immune IgG effector responses in humans
(2016-05-18)t IgG responses are fundamental to adaptive immunity and document immunological memory of previous pathogen encounter. While specific antigen recognition is mediated by the variable F(ab′)2 domain of IgG, various effector ...