Browsing Microbiología by Title
Now showing items 371-390 of 809
-
Genetic variation of the Y chromosome in Chibcha-Speaking amerindians of Costa Rica and Panama
(Human Biology 77(1): 71-91, 2005)Genetic variation of the Y chromosome in five Chibchan tribes (Bribri, Cabecar, Guaymi, Huetar, and Teribe) of Costa Rica and Panama was analyzed using six microsatellite loci (DYS 19, DYS389A, DYS389B, DYS390, DYS391, and ... -
Genetic, dietary, and other lifestyle determinants of serum homocysteine levels in young adults in Costa Rica
(2005)Objective: Elevated serum total homocysteine (tHcy) is considered an independent risk factor for cardiovascular disease. The objective of this study was to develop the first-ever information on the prevalence of ... -
Geographical variability of the venoms of four populations of Bothrops asper from Panama: Toxicological analysis and neutralization by a polyvalent antivenom
(2017-06)Bothrops asper is the medically most important venomous snake in Central America. In Panama, the country having the highest incidence of snakebites in Latin America, B. asper is widely distributed throughout the country ... -
Global genetic diversity of Aedes aegypti
(2016-11)Mosquitoes, especially Aedes aegypti, are becoming important models for studying invasion biology. We characterized genetic variation at 12 microsatellite loci in 79 populations of Ae. aegypti from 30 countries in six ... -
Group-II phospholipase A2 enzymes
(2015-05)Phospholipase A2 are esterolytic enzymes that catalyze the hydrolysis of 1,2-diacyl-3-sn-glycerophospholipids at the C2 position, resulting in the formation of lysophospholipids and free fatty acid. They constitute one of ... -
Hacia una mayor integración de las ciencias naturales y las ciencias sociales: análisis de un caso relacionado con un problema de salud pública
(2009)Se discute la conveniencia de promover una interacción y un diálogo productivo entre las ciencias naturales, las ciencias sociales y las tecnologías. El tema se analiza alrededor del caso de un problema de salud: los ... -
Hemorrhage Caused by Snake Venom Metalloproteinases: A Journey of Discovery and Understanding
(2016-03-26)The historical development of discoveries and conceptual frames for understanding the hemorrhagic activity induced by viperid snake venoms and by hemorrhagic metalloproteinases (SVMPs) present in these venoms is reviewed. ... -
Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damage
(2005-06-15)Zinc-dependent metalloproteinases are responsible for the hemorrhagic activity characteristic of viperid snake venoms. Snake venom metalloproteinases (SVMPs) are classified in various groups (P-I–IV), according to their ... -
Hemostatic effects induced by Thalassophryne nattereri fish venom: a model of endothelium-mediated blood flow impairment.
(2002-08)Accidents by Thalassophryne nattereri fish venom are characterised by severe local symptoms and signs including pain of fast onset, oedema and necrosis with impaired muscle regeneration. These effects have been related to ... -
Heterogeneidad clonal en epimastigotos de una cepa centroamericana de Trypanosoma cruzi (Kinetoplastida: Trypanosomatidae)
(2002)El fenómeno de heterogeneidad clonal fue evaluado en una cepa centroamericana de Trypanosoma cruzi (San Salvador) en un sistema de cultivo en macrófagos. Cuatro clones denominados Clon 9, Clon 10, Clon 11 y Clon 12 fueron ... -
High resolution analysis of snake venom metalloproteinase (SVMP) peptide bond cleavage specificity using proteome based peptide libraries and mass spectrometry
(2011-04-01)Both serine and metalloproteinases have been shown to play the role of toxins in the venoms of many snakes. Determination of the natural protein substrates of these toxins is an important feature in the toxinological ... -
High-density peptide microarray exploration of the antibody response in a rabbit immunized with a neurotoxic venom fraction
(2017-11)Polyvalent snakebite antivenoms derive their therapeutic success from the ability of their antibodies to neutralize venom toxins across multiple snake species. This ability results from a production process involving ... -
High-Resolution Crystal Structure of the Snake Venom Metalloproteinase BaP1 Complexed with a Peptidomimetic: Insight into Inhibitor Binding
(2009-07-07)BaP1, a zinc-dependent endopeptidase belonging to the P-I class of snake venom metalloproteinases, exerts multiple tissue-damaging activities, leading to hemorrhage, myonecrosis, dermonecrosis, blistering, and edema. ... -
High-throughput immuno-profiling of mamba (Dendroaspis) venom toxin epitopes using high-density peptide microarrays
(2016-11-08)Snakebite envenoming is a serious condition requiring medical attention and administration of antivenom. Current antivenoms are antibody preparations obtained from the plasma of animals immunised with whole venom(s) and ... -
Highly individual patterns of virus‑immune IgG effector responses in humans
(2016-05-18)t IgG responses are fundamental to adaptive immunity and document immunological memory of previous pathogen encounter. While specific antigen recognition is mediated by the variable F(ab′)2 domain of IgG, various effector ... -
Histopathological and biochemical alterations induced by intramuscular injection of Bothrops asper (terciopelo) venom in mice
(1989)The local and systemic pathological changes induced by an i.m. injection of 100 micrograms of Bothrops asper venom in mice were studied histologically and by following the changes in serum levels of enzymes, proteins, ATP ... -
La Homocisteína como nuevo factor de riesgo cardiovascular
(2004)En la actualidad se tiene un amplio conocimiento de los factores de riesgo asociados con esta enfermedad. Sin embargo, las causas que inducen el inicio del proceso patológico aún son motivo de discusión. Los factores de ... -
Homogenates of skeletal muscle injected with snake venom inhibit myogenic differentiation in cell culture
(2013-02)Introduction: Viperid snakebite envenomings are characterized by muscle necrosis and a deficient regenerative response. Methods: Homogenates from gastrocnemius muscles of mice injected with the venom of the snake Bothrops ... -
Horse IgG isotypes and cross-neutralization of two snake antivenoms produced in Brazil and Costa Rica
(2000-05)Horse IgG isotypes and cross-neutralization of two snake antivenoms produced in Brazil and Costa Rica. Toxicon 000–000. This work compared the specificity, ELISA titers and IgG subclass content of the polyvalent antivenom ...