Browsing Microbiología by Author "af7d77ac-9027-41ec-b584-c6e58eda8df0"
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Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities
Quesada Gómez, Carlos; López Ureña, Diana; Chumbler, Nicole; Kroh, Heather K.; Castro Peña, Carolina; Rodríguez Sánchez, César; Orozco Aguilar, Josué; González Camacho, Sara María; Rucavado Romero, Alexandra; Guzmán Verri, Caterina; Lawley, Trevor D.; Lacy, D. Borden; Chaves Olarte, Esteban (2016-03)Clostridium difficile strains within the hypervirulent clade 2 are responsible for nosocomial outbreaks worldwide. The increased pathogenic potential of these strains has been attributed to several factors but is still ... -
Proteogenomic analysis of the Clostridium difficile exoproteome reveals a correlation between phylogenetic distribution and virulence potential
Quesada Gómez, Carlos; Murillo Corrales, Tatiana; Arce, Grettel; Badilla Lobo, Adriana; Castro Peña, Carolina; Molina Mora, José Arturo; López Ureña, Diana; González Camacho, Sara María; Lomonte, Bruno; Chacón Díaz, Carlos; Rodríguez Sánchez, César; Chaves Olarte, Esteban (2020)C. difficile induces antibiotic-associated diarrhea due to the action of two secreted toxins, TcdA and TcdB. A considerable range of virulence among C. difficile strains has been widely reported. During a hospital outbreak, ...