Browsing Microbiología by Author "64833ce4-8ec6-47c5-940d-3c16a4307390"
Now showing items 1-7 of 7
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A first perturbome of Pseudomonas aeruginosa: Identification of core genes related to multiple perturbations by a machine learning approach
Molina Mora, José Arturo; Montero Manso, Pablo; García Batan, Raquel; Campos Sánchez, Rebeca; Vilar Fernández, José; García Santamaría, Fernando (2021)Tolerance to stress conditions is vital for organismal survival, including bacteria under specific environmental conditions, antibiotics, and other perturbations. Some studies have described common modulation and shared genes ... -
Avances de la bioinformática en Costa Rica: Vista retrospectiva y perspectivas
Campos Sánchez, Rebeca; Flores Cruz, Andrés; Molina Mora, José Arturo; Mora Rodríguez, Rodrigo Antonio; Rodríguez Sánchez, César; Gatica Arias, Andrés Mauricio; Guzmán Verri, Caterina (2021-11-09)Introducción: La disciplina científica de la bioinformática tiene el potencial de generar aplicaciones innovadoras para las sociedades humanas. Costa Rica, pequeña en tamaño y población en comparación con otros países de ... -
Gene expression analyses of gingival tissue of patients with periodontitis using public transcriptomic data
Molina Mora, José Arturo; Campos Sánchez, Rebeca; Castro Mora, Milena; Silva de la Fuente, Sandra Maria (2022-11)Abstract—Periodontal disease (PD) is a multifactorial and chronic condition of infection and inflammation of the gingival tissue. However, many of the biological and molecular mechanisms regarding the development of this ... -
Gene Expression Dynamics Induced by Ciprofloxacin and Loss of LexA Function in Pseudomonas aeruginosa PAO1 Using Data Mining and Network Analysis
Molina Mora, José Arturo; Campos Sánchez, Rebeca; García Santamaría, Fernando (2018)Pseudomonas aeruginosa is an opportunistic pathogen that causes a variety of infections in humans and frequently develops mechanisms of resistance to antibiotics, which makes its treatment difficult. In this study we ... -
High quality 3C de novo assembly and annotation of a multidrug resistant ST-111 Pseudomonas aeruginosa genome: Benchmark of hybrid and non-hybrid assemblers
Molina Mora, José Arturo; Campos Sánchez, Rebeca; Rodríguez Sánchez, César; Shi, Leming; García Santamaría, Fernando (2020)Genotyping methods and genome sequencing are indispensable to reveal genomic structure of bacterial species displaying high level of genome plasticity. However, reconstruction of genome or assembly is not straightforward ... -
Transcriptomic determinants of the response of ST-111 Pseudomonas aeruginosa AG1 to ciprofloxacin identified by a top-down systems biology approach
Molina Mora, José Arturo; Chinchilla Montero, Diana; Chavarría Azofeifa, Maribel; Ulloa Morales, Alejandro J.; Campos Sánchez, Rebeca; Mora Rodríguez, Rodrigo Antonio; Shi, Leming; García Santamaría, Fernando (2020)Pseudomonas aeruginosa is an opportunistic pathogen that thrives in diverse environments and causes a variety of human infections. Pseudomonas aeruginosa AG1 (PaeAG1) is a high-risk sequence type 111 (ST-111) strain isolated ...