Browsing Microbiología by Author "59a10b4b-66d5-4aab-bfbb-2fd3c126bda7"
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Biochemical characterization of the venom of Central American scorpion Didymocentrus krausi Francke, 1978 (Diplocentridae) and its toxic effects in vivo and in vitro
Rojas Azofeifa, Daniela; Sasa Marín, Mahmood; Lomonte, Bruno; Diego García, Elia; Ortiz Chaves, Natalia; Bonilla Murillo, Fabián; Murillo Masís, Renato; Tytgat, Jan; Díaz Oreiro, Cecilia (2019)non-buthid venoms, for which knowledge is scarce. In this work, we characterized the venom of a Diplocentridae species, Didymocentrus krausi, a small fossorial scorpion that inhabits the Tropical Dry Forest of Central ... -
Identification of New Snake Venom Metalloproteinase Inhibitors Using Compound Screening and Rational Peptide Design
Villalta Romero, Fabián; Gortat, Anna; Herrera, Andrés E.; Arguedas, Rebeca; Quesada Espinoza, Francisco Javier; Lopes de Melo, Robson; Calvete Chornet, Juan José; Montero Villalobos, Mavis Lili; Murillo Masís, Renato; Rucavado Romero, Alexandra; Pérez Payá, Enrique (2012)The majority of snakebite envenomations in Central America are caused by the viperid species Bothrops asper, whose venom contains a high proportion of zinc-dependent metalloproteinases that play a relevant role in the ... -
Inhibitory effects of Piper umbellatum and Piper peltatum extracts towards myotoxic phospholipases A2 from Bothrops snake venoms: isolation of 4-nerolidylcatechol as active principle
Núñez Rangel, Vitelbina; Castro Araya, Víctor H.; Murillo Masís, Renato; Ponce Soto, Luis Alberto; Merfort, Irmgard; Lomonte, Bruno (2005)Phospholipases A2 (PLA2) are important constituents of snake venoms, being responsible for several of their toxic actions. Extracts from plants used in folk medicine were screened for inhibition of the enzymatic activity ...