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Mineral Trioxide Aggregate and Calcium Hydroxide Promotes In Vivo Intratubular Mineralization

dc.creatorReyes Carmona, Jessie
dc.creatorSantos, Adair
dc.creatorCordeiro, Mabel
dc.date2016-03-17
dc.date.accessioned2016-05-02T22:19:11Z
dc.date.available2016-05-02T22:19:11Z
dc.identifierhttp://revistas.ucr.ac.cr/index.php/Odontos/article/view/23548
dc.identifier10.15517/ijds.v0i0.23548
dc.identifier.urihttps://hdl.handle.net/10669/21383
dc.descriptionLiterature showed that the interaction of Mineral Trioxide Aggregate (MTA) with dentin in phosphate-buffered saline (PBS) promotes a biomineralization process that leads to the formation of an interfacial layer with mineralized structures at the cement-dentin interface. Thus, we investigated the in vivo biomineralization process promoted by MTA and Ca(OH)² with dentin. Human dentin tubes filled with ProRoot MTA, Ca(OH)²  or kept empty were implanted in subcutaneous tissues in the back of mice. After 12h, 1, 3, 7, 15, 30 and 60 days, the dentin tubes were processed for Scanning Electron Microscope (SEM) observations. SEM examination showed the presence of apatite-like clusters on collagen fibrils over the surface of tubes containing the biomaterials. This mineral deposition was more extensive and compact through time. At day 7, a compact layer of apatite was formed. The MTA/Ca(OH)² -dentin interface showed intratubular mineralization as early as 12h post-implantation. MTA and Ca(OH)²  in an in vivo environment promoted a biomineralization process with dentin, simultaneously to the acute inflammatory response. MTA triggered an earlier and denser interfacial layer. en-US
dc.formatapplication/pdf
dc.formattext/html
dc.languageeng
dc.publisherUniversidad de Costa Ricaen-US
dc.relationhttp://revistas.ucr.ac.cr/index.php/Odontos/article/view/23548/23995
dc.rightsCopyright (c) 2016 Odovtos - International Journal of Dental Sciencesen-US
dc.sourceOdovtos International Journal of Dental Sciences; Vol 18, No 1 (2016): Odovtos - International Journal of Dental Sciences V.18, 1; 49-59es-ES
dc.sourceOdovtos - International Journal of Dental Sciences; Vol 18, No 1 (2016): Odovtos - International Journal of Dental Sciences V.18, 1; 49-59en-US
dc.source2215-3411
dc.source1659-1046
dc.source10.15517/ijds.v18i1
dc.titleMineral Trioxide Aggregate and Calcium Hydroxide Promotes In Vivo Intratubular Mineralizationen-US
dc.typeartículo original


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