Role of the CTX Test for Evaluation of the Risk in Diagnostic and Treatment of the Osteonecrosis of the Jaws Induced by the use of Bisphosphonates

Lorz Ulloa, Patricia; Varela, Rodolfo

dc.creator	Lorz Ulloa, Patricia
dc.creator	Varela, Rodolfo
dc.date	2015-11-29
dc.date.accessioned	2016-05-02T22:18:55Z
dc.date.available	2016-05-02T22:18:55Z
dc.identifier	http://revistas.ucr.ac.cr/index.php/Odontos/article/view/22044
dc.identifier	10.15517/ijds.v0i0.22044
dc.identifier.uri	https://hdl.handle.net/10669/21312
dc.description	A literature review was conducted to determine the effectiveness of the C-terminal crosslinking telopeptide (CTX) serologic test, which has been suggested to predict the risk of developing osteonecrosis of the jaw in patients taking oral bisphosphonates. Osteonecrosis of the jaw (ONJ) is a condition that causes avascular necrosis of the alveolar bone, which occurs in patients treated with bisphosphonates. It has been suggested that a CTX value below 100 pg/ml represents a high risk for ONJ , while between 100 and 150 pg / ml a moderate risk and above 150pg/ml minimal risk. The CTX test has been controversial and it has not been possible to frame it as strong evidence, since several studies have found variable results. Patients with very low CTX levels have not developed ONJ, and others with very high CTX levels, supposedly safe, have done . CTX test is a useful test to inform the dentist about the activity level on patient ́s bone turnover, and may be useful to advise the patient. Low CTX levels could serve to delay a surgical procedure that is not deemed urgent.	es-ES
dc.format	application/pdf
dc.language	spa
dc.publisher	Universidad de Costa Rica	en-US
dc.rights	Copyright (c) 2015 Odovtos - International Journal of Dental Sciences	en-US
dc.source	Odovtos International Journal of Dental Sciences; Vol 17, No 1 (2015): Odovtos - International Journal of Dental Sciences; 41-51	es-ES
dc.source	Odovtos - International Journal of Dental Sciences; Vol 17, No 1 (2015): Odovtos - International Journal of Dental Sciences; 41-51	en-US
dc.source	2215-3411
dc.source	1659-1046
dc.source	10.15517/ijds.v17i1
dc.title	Role of the CTX Test for Evaluation of the Risk in Diagnostic and Treatment of the Osteonecrosis of the Jaws Induced by the use of Bisphosphonates	es-ES
dc.type	artículo original

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