Epidemiology of rotaviruses in a cohort of 45 Guatemalan Mayan Indian children observed from birth to the age of three years
Simhon Edgar, Alberto
Urrutia, Juan José
Kronmal, Richard A.
MetadatosMostrar el registro completo del ítem
Chort of 45 children was observed from birth to three years of age in their natural ecosystem to determine patterns of infection, morbidity, and growth. Data from enzyme-linked immunosorbent assay analysis for rotavirus of 5,891 extracts (kept frozen since 1964-1969) of weekly fecal specimens were compared against growth, morbidity, and specimen data files, permitting a retrospective description of the epidemiology of rotavirus infection in the cohort. Rotavirus infections were uncommon in the first months of life in intensively breast-fed infants. Infection increased with age to reach a maximal rate in the six- to 18-month age period. While there was a high incidence of diarrhea in the cohort, rotavirus was associated with only 10% of such episodes. The incidence of rotavirus infection was 1.2 episodes per child-year, and the incidence of rotavirus-associated diarrhea was 0.8 episodes per child-year. Serious outbreaks of rotavirus generally occurred from September through December, with as many as one-half of the children becoming infected. Repeated rotavirus infection was a common phenomenon.
Enlace externo al ítemdoi: 10.1093/infdis/148.3.452
Artículo científico -- Universidad de Costa Rica. Instituto de Investigaciones en Salud, 1983. Este artículo es privado debido a limitaciones de derechos de autor.
- Microbiología