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dc.creatorOcchialini, Alessandra
dc.creatorMarais, Armelle
dc.creatorUrdaci, María
dc.creatorSierra Ramos, Rafaela
dc.creatorMuñoz Calero, Nubia
dc.creatorCovacci, Antonello
dc.creatorMégraud, Francis
dc.date.accessioned2015-04-17T15:47:18Z
dc.date.available2015-04-17T15:47:18Z
dc.date.issued2001-03
dc.identifier.citationhttp://iai.asm.org/content/69/3/1902.fulles_ES
dc.identifier.issn0019-9567
dc.identifier.urihttp://hdl.handle.net/10669/11387
dc.descriptionartículo científico -- Universidad de Costa Rica, Instituto de Investigaciones en Salud. 2001es_ES
dc.description.abstractThe composition and in vitro expression of the cag pathogenicity island genes in a group of Helicobacter pylori strains obtained from patients suffering from chronic gastritis-associated dyspepsia (n = 26) or gastric carcinoma (it = 17) were analyzed. No significant difference in the distribution of the 10 studied regions was found between the cases and the controls. Nine strains did not harbor any of the selected regions: eight (30.8%) isolated from patients with gastritis only and one (5.9%) from a patient with gastric carcinoma. No association was found between the number of repeated sequences at the 3' end of the cagA gene or the presence of tyrosine phosphorylation motifs and the clinical origin of the strains. The virBIO homolog gene was the sole gene studied to be significantly expressed more often in cancer strains than in gastritis strains (P = 0.03)es_ES
dc.description.sponsorshipinfo:eu-repo/grantAgreement/Universidad de Costa Rica/Instituto de Investigaciones en Salud//Costa Rica//es_ES
dc.language.isoeses_ES
dc.publisherInfection Immunity 69 (3) 1902-1908es_ES
dc.sourceInfection and Immunity 69(3):1902-1908es_ES
dc.subjectHelicobacter pylories_ES
dc.subjectchronic gastritis-associatedes_ES
dc.subjectGenéticaes_ES
dc.subjectGenética humanaes_ES
dc.subjectGeneticses_ES
dc.titleComposition and Gene Expression of the cag Pathogenicity Island in Helicobacter pylori Strains Isolated from Gastric Carcinoma and Gastritis Patients in Costa Ricaes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.identifier.doidoi: 10.1128/IAI.69.3.1902-1908.2001
dc.description.procedenceUCR::Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA)es_ES


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